PROGRAM

Valencia 2nd - 5th December 2025

14:00-17:00
Registration
14:45-15:00
Opening remarks
15:00-16:00
Inaugural Talk
15:00-16:00

"A pan-genomic view of new gene evolution"

Howard  Ochman

University of Texas at Austin, USA

16:00-18:00
Session 1: Introduction to global pangenomes for One Health
16:00-16:30

“Infectious diseases, zoonoses, therapeutics… Are we doomed? Pwn3d-genome to the rescue!”

Hervé Tettelin

University of Maryland School of Medicine, USA


16:30-17:00

"Mapping Microbial Diversity and Resistance Gene Burden in Global Food Metagenomes"

Avelino Álvarez Ordóñez

University of Leon, Spain


17:00-17:30

"From pangenomes and strain diversity to the functional diversity of commensal microbes"

Till Strowig

Helmholtz Centre for Infection Research, Germany


17:30-18:00

Short talks

17:30-17:45 Biofilm-associated genes encoding amyloids are part of the accessory genome of the pathobiome. 
    Ainara Aginaga Etxamendi, Instituto de Agrobiotecnología (IDAB-CSIC), Spain. 

17:45-18:00 Fecal carriage of ESBL-producing E. coli and genetic characterization in rural children and livestock in the Somali region, Ethiopia: a one health approach. 
     Muhummed Abdifatah Muktar, University of Lausanne, Switzerland. 

18:00-20:00
Welcome cocktail
09:00-13:00
Session 2: Evolution of the pangenome and environmental interactions
09:00-09:30

"Uncovering hidden diversity: Pangenomics of rhizosphere bacteria and their role in environmental and host health"

Zulema Udaondo

National Centre for Biotechnology, Spain


09:30-10:00

"A microbial genome census during the uncultivated data deluge"

Rekha Seshadri

Joint Genome Institute, USA


10:00-10:30

"On the biological meaning of the local pangenome"

Francisco Rodríguez Valera

Miguel Hernandez University, Spain


10:30-11:00

"Coral holobiont bacterial pangenomes in the Anthropocene"

Mónica Medina

University of California Los Angeles, USA


11:00-11:30

Posters and coffee

Posters viewing during coffee break

POSTER LIST


11:30-13:00

Short talks

11:30-11:45 Solving the pangenome paradox: detecting accessory genes under balancing selection in Klebsiella pneumoniae. 
  - Cara Conradsen, The University of Exeter, United Kingdom. 

11:45-12:00 High precision binary trait association on phylogenetic trees. 
  - Ishaq Balogun, Massachusetts Institute of Technology, USA. 

12:00-12:15 Intrinsically disordered protein regions encoded by the Mycobacterium tuberculosis pangenome are fast evolving and contribute to virulence. 
  - Manuela Sironi, University of Milano-Bicocca, Italy. 

12:15-12:30 Accessory no more: plasmid domestication in the plant-associated Pantoea. 
  - Devani Romero Picazo, Christian-Albrechts-Universität, Kiel, Germany. 

12:30-12:45 Gh168 endo-fucanases reveal lineage-specific adaptation to fucoidan-rich niches in Pirellulaceae. 
   - Raquel Liébana García, Fundación AZTI, Spain. 

12:45-13:00 Plastic-degrading enzyme discovery in the Stutzerimonas genus via genome and pangenome analyses. 
   - Anna Luiza Bauer Canellas, Federal University of Rio de Janeiro (UFRJ).

13:00-15:00
Lunch Time
15:00-19:00
Session 3: Interconnected microbiomes and gene exchange
15:00-15:30

"Leveraging mOTUs for Microbiome Comparison Across Hosts and Habitats"

Marija Dmitrijeva

Federal Institute of Technology Zurich, Switzerland


15:30-16:00

“High throughput microbial single-cell genomics for studying interactions of bacteria with their mobile genetic elements”

Maria Dzunkova

University of Valencia, Spain


16:00-16:30

"Plasmid evolution: a (copy) numbers game"

Jerónimo Rodríguez-Beltrán

Ramon y Cajal Health Research Institute, Spain


16:30-17:00

"Immune-deficient bacteria serve as gateways to genetic exchange and microbial evolution"

José Penadés

Imperial College London


17:00-17:30

Posters and coffee

Posters viewing during coffee break

POSTER LIST


17:30-19:00

Short talks

17:30-17:45 Circulation of carbapenem resistance plasmids between hospital and aquatic environments at the scale of a coastal river basin. 
   - Stéphanie Bedhomme, Centre d'Ecologie Fonctionnelle et Evolutive, France. 

17:45-18:00 Cliquebait : detecting clades living at the limit (of the 95% ani gap). 
    - Moritz Buck. Swedish University of Agricultural Sciences, Sweden. 

18:00-18:15 Pangene-o-meter: Exploring bacterial genome evolution through gene-content analysis. 
   - Haim Ashkenazy, Max Planck Institute for Biology Tübingen, Germany. 

18:15-18:30 Host-associated mobilome dynamics and pangenome evolution in livestock-associated Staphylococcus aureus. 
   - José Francisco Díaz Méndez, Universidad CEU Cardenal Herrera, Spain. 

18:30-18:45 Enhancing alignment accuracy through core alignment refinement: a comparative tool-based study. 
   - Jordi Sevilla Fortuny, Institut Pasteur, France. 

18:45-19:00 PANGNBANK: A database of pangenome graphs for comparative microbial genomics. 
   - Téo Lemane, CNRS/Genoscope, France. 

09:00-13:00
Session 4: Pangenomic diversity in human and animal microbiomes
09:00-09:30

"One Health Microbiome"

Pascale Vonaesch

University of Lausanne, Switzerland


09:30-10:00

"Environmental Microbiome and One Health: Exploring the Interface Between Livestock and Ecosystem Health"

Laura Lorenzo Rebenaque

Institute of Science and Animal Technology, Universitat Politècnica de Valencia, Spain 


10:00-10:30

"Assessment of the acquisition and transmission of the microbiome through strain-level profiling: a One Health perspective"

Mireia Vallès-Colomer

Pompeu Fabra University, Spain


10:30-11:00

“Leveraging the vaginal metapangenome to design next-generation live biotherapeutic products for women’s health”

Jacques Ravel

University of Maryland School of Medicine, USA


11:00-11:30

Posters and coffee

Posters viewing during coffee break

POSTER LIST


11:30-13:00

Short talks

11:30-11:45 Mapping the pangenome functional landscape with protein language models links bacterial genetic diversity to host proteostasis. 
   - Daniel Martínez Martínez, MRC Laboratory of Medical Sciences (LMS), United Kingdom. 

11:45-12:00 Fusobacterum animalis core genes rather than virulence operons may underlie oncogenic potential. 
   - Manuela Sironi, University of Milano-Bicocca, Italy. 

12:00-12:15 Phage activation and genome decay under chemotherapy shape skin microbiome evolution. 
   - Zaki Saati Santamaría, University of Salamanca, Spain. 

12:15-12:30 Escherichia coli isolated in maternal-infant environment: an in-depth perspective from genome to function. 
   - Manuel Bernabeu. Institute of Agrochemistry and Food Technology, National Research Council (IATA-CSIC), Spain. 

12:30-12:45 A decade of experience mapping the microbiota in enteric infections and searching for novel solutions through competitive exclusion. 
   - Hector Arguello-Rodríguez, Universidad de León, Spain. 

12:45-13:00 Antibiotic-resistant bacteria decolonization through fecal microbiota transplantation facilitates de novo generation of multidrug-resistant organisms in mice. 
  - Candela Fuster González, FISABIO Foundation, Spain. 

13:00-15:00
Lunch time
15:00-19:00
Session 5: The pangenome in infectious diseases
15:00-15:30

When Names lie: Taxonomic turbulence and pangenome diversity in the Enterobacteriaceae.

David Ussery

Oklahoma State University, USA


15:30-16:00

"Integrons, a shared toolbox against phages and antibiotics"

José Antonio Escudero

Complutense University of Madrid, Spain


16:00-16:30

Whole genome sequencing of veterinary pathogens for an improved antimicrobial stewardship

Lourdes Migura-García

Institute of Agrifood Research and Technology, Spain


16:30-17:00

Integrating accessory genomic elements into infectious disease epidemiology

Mathew Beale

Sanger Institute, United Kingdom


17:00-17:30

Posters and coffee

Posters viewing during coffee break

POSTER LIST


17:30-19:00

Short talks

17:30-17:45 What do we really know about leprosy? New insights from early medieval and roman genomes. 
   - Marta Pla Díaz, University of Basel, Switzerland. 

17:45-18:00 Analysis of the global group b Streptococcus pangenome: insights into genetic diversity and evaluation of potential vaccine targets. 
   - Nida Javaid, Wellcome Sanger Institute, United Kingdom. 

18:00-18:15 Large-scale study of the Neisseria gonorrhoeae pangenome: population structure and antimicrobial resistance. 
   - Andrea Sánchez-Serrano, FISABIO Foundation, Spain. 

18:15-18:30 Genomic association of sars-cov-2 severity during the omicron wave. 
   - Mireia Coscollá Devís, ‪I2SysBio, University of Valencia, Spain. 

18:30-18:45 A pangenomic view of Mycobacterium tuberculosis ecotypes and host? Range determinants. 
   - Paula Ruiz Rodríguez, ‪I2SysBio, University of Valencia. Spain. 

18:45-19:00 Pangenome analysis of a complex vancomycin-resistant Enterococcus faecium outbreak in the Comunitat Valenciana. 
   - Carlos Valiente Mullor, FISABIO Foundation – University of Valencia, Spain. 

 


19:00-19:30

Best Sequencing project

19:00-19:15 Mining the cazome of seaweed-associated bacteria from the Brazilian coast for new industrial biocatalysts.  
   - Bruno de Oliveira, Fluminense Federal University, Brazil. 

19:15-19:30 A Mycobacterium tuberculosis pangenome during infection to shed light on the pathogenesis of drug-resistant tuberculosis. 
   - Ana María García Marín, Biomedicine Institute of Valencia, Spain. 

21:00-24:00
Social Dinner
09:00-13:00
Session 6: The role of phages: from community dynamics to phage therapy
09:00-09:30

“Deciphering and targeting the virome”

David Páez-Espino

Ancilia Bio, USA


09:30-10:00

“Exploring the co-evolutionary arms race between bacteria and phages”

Rafael Pinilla-Redondo

University of Copenhagen, Denmark


10:00-10:30

Using evolutionary genomics of phage-bacteria interactions to advance biotechnology

Paul Turner

Yale University, USA


10:30-11:00

“Phage therapy as personalized medicine against bacteria”

Pilar Domingo

University of Valencia, Spain


11:00-11:30

Poster and coffe

Poster viewing during coffee break

POSTER LIST


11:30-12:15

Short talks

11:30-11:45 From pioneers to persistence: breastfeeding and maternal reservoirs shape infant gut phageome maturation. 
   - Elena Cabello Yeves, Biomedicine Institute of Valencia (IBV-CSIC), Spain. 

11:45-12:00 The origins and evolution of cyanomyophages infecting picocyanobacteria: a conundrum spanning the salinity divide. 
    - Pedro J. Cabello-Yeves, University of Warwick, United Kingdom. 

12:00-12:15 Mobile elements and phages as key drivers of genome architecture variability in Bacillus thuringiensis subsp. israelensis and their comparison with B. thuringiensis subsp. kurstaki. 
   - Raida Zribi-Zghal, Centre of Biotechnology of Sfax, Tunisia. 

12:15-13:00
Prizes, final notes and closure.

Contact

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